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Missions are endless in Marapets, you can keep doing missions endlessly and receive the same prizes every time. The only progressive mission would be the Troll one, every time you complete it you're asked to be an additional level for each instrument. Some instruments are worth a million marapoints so for some people it's not a good idea to complete it more than once. If you have the will and the marapoints to continue to do it, by all means you should.